Because of the pitfalls of dependancy, abuse, and misuse with opioids, even at advisable doses [see Warnings and Safeguards (five.one)], reserve promethazine HCl and codeine phosphate oral solution for use in adult individuals for whom the main advantages of cough suppression are predicted to outwei

If the response to an opioid antagonist is suboptimal or only brief in nature, administer more antagonist as directed from the product or service’s prescribing details. The respiratory depressant results of promethazine are certainly not reversed by opioid antagonists, including naloxone.Alt